Accutane turns off the production of oil within the skin that is believed to be the causative agent in the formation of nodular acne. It\'s quite easy to build up a tolerance to Klonopin with long-term or excessive use wherein the drug will be rendered completely ineffective. Sleep deprivation may result if a person suffers insomnia for a long enough period of time and can present some serious consequences that need to be addressed. Ambien. Serotonin levels control how much blood is allowed to flow through the tiny vessels in the head. Rizatriptan. Maxalt can therefore control this blood flow by controlling how much serotonin is available.